Regression models: Association of high levels (80^th percentile) of serum IgG to selected periodontal species and incident AD.

Model 1: bivariate association with single periodontal antibody. Model 2: controlled for age at phlebotomy (baseline). Model 3: Model 2, also controlled for APOE status, gender, and education. Model 4: Model 3, also controlled for hypertension, smoking, stroke, and diabetes. *Models shown using pseudolikelihood estimator, robust variance estimator, and weight of cases (1), controls (10) [most conservative method]; HR: Hazard ratio. Regression models: Association of high levels (80th percentile) of serum IgG to selected periodontal species and incident AD.