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Severe Schistosomiasis in the Absence of Interleukin-4 (IL-4) Is IL-12 Independent

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PubMed Central2026-05-16 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC97925/
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资源简介:
An interleukin-4 (IL-4)-dependent Th2 response allows wild-type mice to survive infection with the parasite Schistosoma mansoni. In the absence of IL-4, infected mice mount a Th1-like proinflammatory response, develop severe disease, and succumb. Neither the Th1 response nor morbidity is IL-12 dependent in this system.
提供机构:
American Society for Microbiology (ASM)
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