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A pathogen-specific 4mC methyltransferase is critical for epigenetic regulation and virulence of Leptospira interrogans

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NIAID Data Ecosystem2026-03-12 收录
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Transcriptome analysis of a mutant in an orphan methyltranferase revealed global transcriptional regulation of 100 differentially expressed genes. We used RNA-seq to compare the transcriptomes of wild-type L. interrogans with that of the lomA mutant and complemented strains under ideal culture conditions at mid-log phase.

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2020-12-15
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