Additional file 1: of Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics
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Figure S1. Monolayer cultures and generation of ALI-pBEC cultures from non-asthmatics and asthmatics. Figure S2. Viability of HBEC6-KT cell after IAV H1N1 infection at different MOIs. Figure S3. Responses of pBECs from non-asthmatics and asthmatics cultured as monolayers to IAV H1N1 infection. Figure S4. Responses of pBECs from non-asthmatics and asthmatics cultured at ALI to IAV H1N1 infection. Figure S5. RNU44 expression miRNA endogenous control in in pBECs from non-asthmatics and asthmatics cultured as monolayers and at ALI. Figure S6. UV-inactivated IAV H1N1 effects on levels of miRNA expression in pBECs from non-asthmatics and asthmatics. Figure S7. miR-22 mimic suppresses and antagomir increases CD147 and HDAC4 mRNA expression. (ZIP 499 kb)
