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Transcriptome analysis of murine Hdac2 knockout pancreatic tumor cells.. HDAC in PDAC

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NIAID Data Ecosystem2026-03-11 收录
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We performed a knockout of Hdac2 in a dual recombinase system based and KrasG12D/+ driven mouse model of pancreatic ductal adenocarcinoma (n=3 biological; n= 2 technical replicates).Tamoxifen (4-OHT) treatment for 8 days excised the floxed Hdac2 alleles by the CreERT2 fusion protein. Ethanol (EtOH) served as a vehicle control. Genotype: FSF-KrasG12D/+, FSF-Trp53del/+, Pdx1-Flp, R26CAG-FSF-CreERT2/+, Pdk1loxP/+, Hdac2loxP/loxP

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2020-03-23
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