Functional MRI data from medetomidine-isoflurane anesthetized marmosets

This dataset contains unprocessed functional MRI (fMRI) data acquired in common marmosets (Callithrix jacchus), The data were obtained during a continuous infusion of the sedative medetomidine, supplemented with a low concentration of isoflurane. All experiments were carried out in accordance with the guidelines from Directive 2010/63/EU of the European Parliament on the protection of animals used for scientific purposes. Related paper This dataset supplements the following manuscript. Preserving functional network structure under anesthesia in the marmoset monkey brain M Ortiz-Rios, N Sirmpilatze, J Koenig, S Boretius - bioRxiv, 2023 doi: https://doi.org/10.1101/2023.11.21.568138 Data structure The main data files are organized into eight zipped folders - sub-02.tar.gz, .... sub-09.tar.gz - each constituting a dataset formatted according to the Brain Imaging Data Structure specifications (BIDS v1.6.0). Each BIDS-formatted dataset contains subfolders for individual sessions (e.g. ses-0001, etc.).Additionally, a text file, participants.tsv, with some essential information about the subjects (e.g. age, weight, sex). Each subject-specific folder contains subfolders named func and anat, storing fMRI and structural MRI data respectively. The (f)MRI data are provided in NIfTI format (suffixed with .nii.gz). The func files are named as {sub-id}_{ses-id}_{run-id}_{task-id}_bold.nii.gz. The task id is based on runs acquired for resting-state or during visual stimulation. BIDS-formatted dataset The basic characteristics of the datasets are given below. More details can be found in the preprint. Marmoset Institution: German Primate Center (Deutsches Primatenzentrum GmbH - Leibniz-Institut für Primatenforschung), Göttingen, Germany MR system: Bruker BioSpec 9.4 T, equpped with B-GA 20S gradient Anatomical MRI scan: Proton density-weighted (PDw) with magnetization transfer (MT) pulse, 1 per subject fMRI scan: GE-EPI, several runs per subject (between 6 and 9 runs), duration 330 s for visual runs and 600 s for resting-state runs, all with a TR of 2 s and a resolution of 0.4 mm isotropic. Subjects: 8 Callithrix jacchus Age range: 2.6 - 9.5 years Weight range: 375 - 517 g Sex: 5 males and 3 females Ethics oversight: Lower Saxony State Office for Consumer Protection and Food Safety, Hannover, Germany (approval numbers 33.19-42502-04-17/2496)