Benchmark results of different compression scenarios in two MCS computation setups (core and genome-scale model of <i>E</i>. <i>coli</i>) for growth-coupled 2,3-BDO synthesis.

The rows “#Genes” and “#GPR rules” refer to the respective number of genes and GPR rules eventually integrated in the network after GPR rule compression (as long as the latter is conducted; otherwise it refers to the original number of genes and GPR rules). Likewise, the rows “#Species”, “#Reactions”,”#Targetable reactions/genes” refer to the numbers of species, reactions, and targetable genes/reactions, respectively, after integration of the (compressed/non-compressed) GPR rules and/or after network compression.