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Dataset from: "Plasticity in voltage-gated ion channels following overwintering in respiratory motoneurons of American bullfrogs"

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https://figshare.com/articles/dataset/Dataset_from_Plasticity_in_voltage-gated_ion_channels_following_overwintering_in_respiratory_motoneurons_of_American_bullfrogs_/27018346
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For a full description of the methods, please check the original paper. Below, please find a description of the files' content. Files on firing rates: Hypoglossal_firing rate, Fast vagus_firing rate, Slow vagus_firing rate Treatment: control and overwintered frogs Current: input current (in picoamperes: pA) utilized during current clamp experiments to elicit neuronal firing rates Firing rate: neuron firing rate (in hertz: Hz) elicited by each input current used Files on membrane properties: Hypoglossal_membrane properties, Fast vagus_membrane properties, Slow vagus_membrane properties Treatment: control and overwintered frogs Resting potential: membrane resting potential (in millivolts: mV) Input resistance: membrane input resistance (in mega Ohm: MΩ) Files on latency and rheobase: Hypoglossal_latency and rheobase, Fast vagus_latency and rheobase, Slow vagus_latency and rheobase Treatment: control and overwintered frogs Latency: latency for first spike (in milli seconds: ms) after current stimulation Rheobase: minimum current (in pico amperes: pA) necessary to elicit a spike in the measured neuron Files on Calcium currents: Hypoglossal_Ca currents, Fast vagus_Ca currents, Slow vagus_Ca currents Treatment: control and overwintered frogs Voltage: voltage (in millivolts: mV) used in voltage clamp experiments eliciting measured currents Peak current: current (in pico amperes normalized by capacitance: pA/pF) measured at the peak response Steady state current: current (in pico amperes normalized by capacitance: pA/pF) measured after the current reached a steady state Files on Potassium currents: Hypoglossal_K currents, Fast vagus_K currents, Slow vagus_K currents Treatment: control and overwintered frogs Voltage: voltage (in millivolts: mV) used in voltage clamp experiments eliciting measured currents Total current: total potassium current (in pico amperes normalized by capacitance: pA/pF) measured High threshold current: high threshold potassium current (in pico amperes normalized by capacitance: pA/pF) measured A-current: potassium A-current (in pico amperes normalized by capacitance: pA/pF), calculated by subtracting high threshold currents from total current Files on sodium persistent inward currents (NaPIC): Hypoglossal_Na persistent inward currents, Fast vagus_Na persistent inward currents, Slow vagus_Na persistent inward currents Treatment: control and overwintered frogs Holding current: in pico amperes normalized by capacitance (pA/pF) Current amplitude: difference between the holding current and the peak response (in pico amperes normalized by capacitance: pA/pF) Peak voltage: voltage (in milli volts: mV) where the current peak response was identified Voltage sensitivity: the slope (in pico amperes over milli volts: pA/mV) of the change in current (in pico amperes: pA) by the change in voltage (in milli volts: mV)
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2025-03-17
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