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Multi-omics study of Indian ovarian cancer samples

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https://www.ncbi.nlm.nih.gov/sra/SRP414459
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From the current study we found population specific and novel variants in tumour specific context. Integrated exome and transcriptome revealed CIITA, MUC4 and MUC16 as possible drivers due to elevated expression as well as mutational hits in the Indian cohort. To summarise, analysing exome transcriptome and splicing patterns revealed different molecular signatures in the ovarian cancer histotypes of the Indian cohort, implying the need for a multi omics approach for prognostic and diagnostic purposes.
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2023-06-12
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