Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI87

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI87 Descriptor: 3C-like proteinase nsp5, benzyl [(2S,3R)-3-tert-butoxy-1-{[(2S)-3-cyclohexyl-1-oxo-1-(2-{[(3S)-2-oxopyrrolidin-3-yl]methyl}-2-propanoylhydrazinyl)propan-2-yl]amino}-1-oxobutan-2-yl]carbamate (non-preferred name) Authors: Blankenship, L.R, Yang, K.S, Liu, W.R. Deposit date: 2021-10-08 Release date: 2023-04-12 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.85 Å) Cite: An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease. Biorxiv, 2023