Crystals structure of Human Glucokinase in complex with small molecule activator

Crystals structure of Human Glucokinase in complex with small molecule activator Descriptor: (2S)-2-{[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy}-N-(5-chloropyridin-2-yl)-3-(2-hydroxyethoxy)propanamide, Glucokinase isoform 3, SODIUM ION, ... Authors: Ogg, D.J, Hargreaves, D, Gerhardt, S, Flavell, L, McAlister, M. Deposit date: 2013-01-24 Release date: 2013-04-24 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets the discovery of AZD3651 and AZD9485 To be Published