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Structure of PKMYT1 bound to inhibitor P32-(R)

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Protein Data Bank Japan2026-07-01 更新2026-07-20 收录
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Structure of PKMYT1 bound to inhibitor P32-(R) Descriptor: (4R)-1-cyclopentyl-4-(3-hydroxyphenyl)-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Authors: Khamrui, S, Lazarus, M.B. Deposit date: 2026-05-13 Release date: 2026-06-10 Last modified: 2026-07-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Allosteric Inhibition of PKMYT1 Induces a Unique, Inactive ATP Binding Site Conformation. J.Am.Chem.Soc., 148, 2026

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2026-05-13
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