M1T1 Streptococcus pyogenes (isolate 5448) WT and Animal-passaged variant in vitro and in vivo

Microarray analysis was performed on in vitro and in vivo-derived RNA from the well characterized S. pyogenes strain 5448 WT and animal-passage variant Cyclic design with dye swap and biological repli

NIAID Data Ecosystem10

RofA Regulon of M1T1 Group A Streptococcus pyogenes 5448

To determine the RofA regulon of M1T1 Group A Streptococcus 5448 grown in THY (rich) media at different phases of growth. WT 5448, a non-polar (Delta)rofA stop codon mutant, and a WT revertant of the

NIAID Data Ecosystem10

Transcriptomic profiling of Streptococcus pyogenes M1T1 strain in a mouse model of necrotizing fasciitis. Streptococcus pyogenes strain:strain 5448

Streptococcus pyogenes is a major cause of necrotizing fasciitis, a life-threatening subcutaneous soft-tissue infection. At the host infection site, the local environment and interaction between host

NIAID Data Ecosystem20

M1T1 Streptococcus pyogenes (isolate 5448) WT and Animal-passaged variant in vitro and in vivo. Streptococcus pyogenes