CRCs in Paramecium tetraurelia.

*Re-annotated CRC sequences were submitted to the EMBL database as TPA (third party annotation) entry. Sequences are available upon publication.**At present only accession numbers from the ParameciumDB (http://paramecium.cgm.cnrs-gif.fr/) are available for CRC-IV-1a sequences. Accession numbers from GeneBank are in progress.CRC-III-1b, printed in grey, is a pseudogene. Scaffold denotes genomic regions according to macronuclear DNA sections as designated in the ParameciumDB.(A) Sequence comparisons within one group. Alignments were performed by ClustalW.Identities of full-length proteins referring to CRC-I-1a (B) or to IP3R type 1 from Mus musculus (C).Identities of C-terminal channel domains (sections are outlined in legend of figure 2B) referring to corresponding sequences of CRC-I-1a (a), of mouse IP3R type 1 (b) or of mouse RyR type 1 (c).