Glioma immune microenvironment associated with malignant transformed cells Transcriptome sequencing

Ribonucleic acid sequencing (RNA-seq) of ihCTC, C12, ihDCTC, ihSTC-BM, precursor mesenchymal stem cells (MSCs) and myeloid-derived suppressor cells (MDSCs) was performed to establish a database of differentially expressed genes (DEGs).This paper intended to find the leader molecules for malignant transformation of these cells, thereby laying a foundation for the development of new molecular targeted therapy.The sequencing cell lines were established in the relevant references. We then performed gene expression profiling analysis using data obtained from RNA-seq of 6 different cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for iTAMD cells (C12, ihCTC, ihDCTC, ihSTC_BM))and its precursor cells (MDSC and MSC).