Dimeric (BRAF)2:(14-3-3)2 complex bound to SB590885 Inhibitor
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Dimeric (BRAF)2:(14-3-3)2 complex bound to SB590885 Inhibitor Descriptor: (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf Authors: Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K. Deposit date: 2021-04-09 Release date: 2022-01-26 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.89 Å) Cite: Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding. Nat Commun, 13, 2022
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2021-04-09
