“Yes” indicates the same extent of cleavage as observed in plasma without inhibitors, “partial” indicates reduced cleavage compared to uninhibited plasma, while “no” indicates that no degradation was

NIAID Data Ecosystem30

Results of Stability study of ALP in human spiked plasma.

药物代谢稳定性

生物标志物分析

Results of Stability study of ALP in human spiked plasma.

NIAID Data Ecosystem30

4‑Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice

抗疟疾药物研发

药物代谢稳定性

Emergence of drug resistant Plasmodium falciparum including artemisinin-tolerant parasites highlights the need for new antimalarials. We have previously shown that dibemequines, 4-amino-7-chloroquinol

NIAID Data Ecosystem30

Metabolic stability data.

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