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The phosphorylation sites in GLI1 analyzed by mass-spec methodology

Name: The phosphorylation sites in GLI1 analyzed by mass-spec methodology
Creator: Zhejinag University
Published: 2023-10-25T12:23:13+08:00

integrated proteome resources2026-02-07 收录

蛋白质磷酸化位点鉴定

Hedgehog信号通路

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The phosphorylation sites in GLI1 analyzed by mass-spec methodology

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提供机构：

Zhejinag University

创建时间：

2023-10-25

Hedgehog信号通路

发育表观遗传学

Purpose: Most Hedgehog responsive gene expression is mediated through GLI de-repression. Additionally GLI -repression is proposed to play roles in limb pre-patterning before HH pathway activation. Thi

NIAID Data Ecosystem30

Acquisition of granule neuron precursor identity and Hedgehog-induced medulloblastoma in mice.

母细胞瘤模型

Hedgehog信号通路

Origins of the brain tumor, medulloblastoma, from stem cells or restricted pro-genitor cells are unclear. To investigate this, we activated oncogenic Hedgehog signaling in multipotent and lineage-rest

NIAID Data Ecosystem30

Additional file 1: of p.E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation

转录因子靶点验证

Hedgehog信号通路

ChIP Primers. Primer sequences used for ChIP validation. (XLSX 11 kb)

Figshare2024-02-15 更新20

Identification BLM phosphosites in presence or absence of lambda phosphatase

蛋白质磷酸化位点鉴定

蛋白翻译后修饰

Identification of BLM phosphosites in presence or absence of lambda phosphatase. DDA analysis of purified protein

NIAID Data Ecosystem30

Crystal structure of the Smoothened CRD, native

蛋白质晶体结构解析

Hedgehog信号通路

Crystal structure of the Smoothened CRD, native Descriptor: SMOOTHENED, SODIUM ION, ZINC ION Authors: Nachtergaele, S, Whalen, D.M, Mydock, L.K, Zhao, Z, Malinauskas, T, Krishnan, K, Ingham, P.W, Cove

Protein Data Bank Japan2024-11-13 更新20

The phosphorylation sites in GLI1 analyzed by mass-spec methodology

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