DYRK2 gene transfer suppresses liver tumorigenesis. DYRK2 gene transfer suppresses liver tumorigenesis
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883685
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We generated liver-specific Dyrk2 knockout mice mating Dyrk2 flox mice with Alb-cre mice and co-introduced SB13-transposase-, myrAkt-, Myc- and mutant Hras-expressing plasmids with either HA- or Dyrk2-expressing plasmid into the knockout mice by HTVi. Dyrk2-expressing suppressed tumorigenesis compared with HA-expressing. Overall design: Total RNAs from Dyrk2-expressed HCC in 3 Dyrk2 LKO mice were compared with Total RNAs from HA-expressed HCC in 3 Dyrk2 LKO mice.
创建时间:
2022-09-23



