Transcriptome sequencing of wounds infected with drug-resistant bacteria treated with hydrogel

Based on the Illumina HiSeq sequencing platform, transcriptome sequencing was performed on the wound tissue samples of rats from the blank group (CK) and the experimental group (H) treated with HB-BCE/Ag after 7 days of treatment. Differentially expressed genes (DEGs) were screened, and analyses of expression levels, expression differences, annotation, and enrichment were carried out. Thus, the biological processes and related signaling pathways associated with DEGs were analyzed, and further, the molecular mechanism of HB-BCE/Ag in treating wound infections was explored.