Germ plasm, the Balbiani body and nuage are evolutionary conserved structures essential for germ cell specification and maintenance. We describe Tdrd6a as a component of these structures with two dist
To better understand the underlying dynamics driving formation of the spermatogonial stem cell (SSC) pool during development, we performed single-cell RNA-sequencing on mouse germ cells isolated from
To investigate the function of Morc1 to chromatin state during gonocyte stage when around 10,000 copies of transposons are deregulated. Overall design: We performed ATAC-seq, RNA-seq, ChIP-seq (for H3
BackgroundThe RNase III endonuclease Dicer is an important regulator of gene expression that processes microRNAs (miRNAs) and small interfering RNAs (siRNAs). The best-characterized function of miRNAs
