Repeatability of pseudo-extracellular volume fraction (α).

Mean and standard deviation (two first columns) of mean, median, mode, standard deviation (std), skewness and kurtosis of α were calculated over all data (n = 22, from 11 volunteers scanned twice). Note that the mean and std over all data were labeled meanall and stdall to avoid confusion with the mean and std of the measurements of C1 and α for each volunteer and scan. Inter- and intra-subject variance (Inter-Var and Intra-Var respectively), coefficient of variation (CV, in %) and intra-class correlation (ICC) were calculated as described in the Statistical analysis section (see text). NA: Not available; the CV is not appropriate for measures (e.g., skewness) that are not inherently non-negative. Symbols represent subjective evaluation of CV and ICC: •• = very good (ICC ⩾ 0.8 or CV ⩽ 10%), • = good (0.6 ⩽ ICC Repeatability of pseudo-extracellular volume fraction (α).