Best SNPs of nuclear regulators of mitochondrial genes (gene set 1) in each sample and linkage disequilibrium between best SNPs of the three different study samples.

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aBMI ≥30 (cases) vs. BMI <25 (controls);
bLocation of SNP: *, exonic;
#,intronic;
§,upstream of gene and.
&,downstream of gene;
cLinkage Disequilibrium (LD) was calculated in the parents of the family-based GWAS sample by use of HaploView 4.2;
dSNP-wise p-values of the meta-analysis were derived by application of the METAL software (for details see ‘Materials and Methods, Meta-analysis’);
fLD between rs7895833 and rs16924888: r2 = 0.581; best gene of each sample and the meta-analysis is indicated in bold letter.
ESRRA, Estrogen related receptor alpha; ESRRG, Estrogen related receptor gamma; GABPA, GA-binding protein alpha subunit; GABPB1, GA-binding protein beta subunit 1; GABPB2, GA-binding protein beta subunit 2; MEF2A, Myocyte-specific enhancer factor 2A; MYC, Myelocytomatosis viral oncogene homolog (avian); NRF1, Nuclear respiratory factor 1; NRIP1, Nuclear receptor-interacting protein 1; PPARA, Peroxisome proliferator-activated receptor alpha; PPARD, Peroxisome proliferator-activated receptor delta; PPARGC1A, Peroxisome proliferator-activated receptor gamma coactivator 1 alpha; PPARGC1B, Peroxisome proliferator-activated receptor gamma coactivator 1 beta; SIRT1, Sirtuin 1; SP1, Specificity protein 1; YY1, Transcriptional repressor protein YY1.