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A Novel Formal Total Synthesis of Cephalotaxine

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NIAID Data Ecosystem2026-03-06 收录
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A formal total synthesis of cephalotaxine (CET), the parent structure of antileukemia Cephalotaxus alkaloids, was achieved through a novel synthesis of the pentacyclic amino enone 4 by a rapid annulation of readily available β-(3,4-methylenedioxy)phenethylamine (2), δ-valerolactone, and bromoacetone.

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2016-05-06
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