Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes

NIAID Data Ecosystem2026-05-01 收录

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Trabectedin药理机制

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https://zenodo.org/record/10477973 数据链接链接失效反馈

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资源简介：

The Source Data for the paper. Each sheet of the Excel file Source_data.xlsx contains source data for a figure panel in the paper.

创建时间：

2024-01-10

Integrated multiomic analysis identifies functional epigenetic signatures regulating nucleotide excision repair (RNA-seq)

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表观遗传调控

Transcription-coupled nucleotide excision repair (TC-NER) is promptly triggered by 'local' elongating RNAP II molecules encountering DNA adducts such as cyclobutane pyrimidine dimers (CPD) induced by

NIAID Data Ecosystem60

Role of Set2 in regulating transcription coupled-nucleotide excision repair. Role of Set2 in regulating transcription coupled-nucleotide excision repair

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组蛋白甲基转移酶功能

Repair of UV damage from the transcribed strand (TS) of yeast genes is rapid due to the transcription coupled nucleotide excision repair (TC-NER) pathway. TC-NER is triggered when RNA polymerase stall

NIAID Data Ecosystem50

Integrated multiomic analysis identifies functional epigenetic signatures regulating nucleotide excision repair (RRBS-seq)

DNA损伤修复表观遗传学

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Transcription-coupled nucleotide excision repair (TC-NER) is promptly triggered by 'local' elongating RNAP II molecules encountering DNA adducts such as cyclobutane pyrimidine dimers (CPD) induced by

NIAID Data Ecosystem30

Integrated multiomic analysis identifies functional epigenetic signatures regulating nucleotide excision repair (RRBS-seq). Integrated multiomic analysis identifies functional epigenetic signatures regulating nucleotide excision repair (RRBS-seq)

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DNA甲基化分析

Transcription-coupled nucleotide excision repair (TC-NER) is promptly triggered by 'local' elongating RNAP II molecules encountering DNA adducts such as cyclobutane pyrimidine dimers (CPD) induced by

NIAID Data Ecosystem50

Integrated multiomic analysis identifies functional epigenetic signatures regulating nucleotide excision repair (RRBS-seq)

DNA损伤修复表观遗传学

转录偶联核苷酸切除修复

Transcription-coupled nucleotide excision repair (TC-NER) is promptly triggered by 'local' elongating RNAP II molecules encountering DNA adducts such as cyclobutane pyrimidine dimers (CPD) induced by

NIAID Data Ecosystem30

Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes

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