In this study, we combine functional assays with multimodal single-cell and bulk profiling to identify functional diversity among TCR-engineered T cells targeting the HER2/neu antigen. We focus on a s
We performed RNA-seq experiments on TNBC tumor tissues from mice treated with EGFR targeted CAR-T therapy or radiotherapy alone and in combination. In brief, we established E0771-EGFR TNBC cell line a
Immunotherapies are beneficial for a considerable proportion of cancer patients, but ineffective in others. In vitro modelling of the complex interactions between cancer cells...
