Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939
收藏Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3kr8
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资源简介：
Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939 Descriptor: 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, GLYCEROL, SULFATE ION, ... Authors: Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) Deposit date: 2009-11-18 Release date: 2009-12-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J.Med.Chem., 53, 2010
创建时间：
2009-11-18
