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Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor Descriptor: Interleukin-1 receptor-associated kinase 4, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide Authors: Ferrao, R, Wu, H. Deposit date: 2018-08-19 Release date: 2019-02-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4). J.Biol.Chem., 294, 2019
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2018-08-19
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