Up-regulated proteins identified by MS or MS/MS and database searches in the hypoxia group.

aProtein spot numbers on 2DE gel. bAccession numbers from NCBI database (accessible at http://www.ncbi.nlm.nih.gov/) or the Swiss-Prot Protein Database (http://web.expasy.org/docs/swiss-prot_guideline.html). cTheoretical molecular mass. dTheoretical PI. eMASCOT protein score (based on combined MS and MS/MS spectra) of greater than 64 (P<0.05) or the total ion score (based on MS/MS spectra) of greater than 30 (P<0.05).