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X-ray co-crystal structure of compound 5 with Mcl-1

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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X-ray co-crystal structure of compound 5 with Mcl-1 Descriptor: (3S)-6'-chloro-5-(cyclobutylmethyl)-3',4,4',5-tetrahydro-2H,2'H-spiro[1,5-benzoxazepine-3,1'-naphthalene]-7-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 Authors: Huang, X. Deposit date: 2019-09-19 Release date: 2019-12-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an alpha-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. J.Med.Chem., 62, 2019

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2019-09-19
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