Pseudomonas aeruginosa Genome sequencing and assembly

In this project, 25 Pseudomonas aeruginosa isolates were collected from 4 patients with ventilator associated infections. 8 of the 25 genomes were fully assembled using Pacbio and Illumina Hi-seq sequencing data, while the other 17 were assembled into draft genomes. We aim to compare these 25 strains to understand if there is any evolution/clonal variation/acquisition of genes along disease progression.