MIGen_ExS: Munich-MI

The Munich-MI study is a case-control cohort study recruited at the German Heart Center in Munich, Germany. It is focused on understanding the genetic contributors to early myocardial-infarction (MI) in the German population. All exome sequencing was performed at the Broad Institute of Harvard and MIT; samples sequence capture was performed using Illumina's ICE Capture reagent and sequencing was performed on an Illumina HiSeq 2000 or 2500.]]>
Cases were recruited from the German Heart Center in Munich, Germany. Cases were defined as men with myocardial infarction (MI) before age 41 and women with MI before age 56. Controls were selected from German population studies and were individuals without MI or coronary artery disease (CAD) over age 65 and 75 for men and women, respectively.]]>