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Isolation and Structure Elucidation of Pentahydroxyscirpene, a Trichothecene <i>Fusarium</i> Mycotoxin

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NIAID Data Ecosystem2026-03-09 收录
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Pentahydroxyscirpene, a novel trichothecene-type compound, was isolated from Fusarium-inoculated rice. The structure of pentahydroxyscirpene was elucidated by 1D and 2D NMR spectroscopy and X-ray single-crystal diffraction. The conformation in solution was determined by NOESY experiments supported by quantum chemical calculations. In vitro toxicity tests showed that pentahydroxyscirpene inhibits protein synthesis as do other trichothecenes.

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2015-12-17
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