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Crystal structure of the bromodomain of human Ep300 bound to the inhibitor XDM3d

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Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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Crystal structure of the bromodomain of human Ep300 bound to the inhibitor XDM3d Descriptor: ACETATE ION, Histone acetyltransferase p300, ~{N}-[(1~{S},2~{S})-7-chloranyl-2-oxidanyl-1,2,3,4-tetrahydronaphthalen-1-yl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole -2-carboxamide Authors: Huegle, M, Wohlwend, D, Gerhardt, S. Deposit date: 2016-08-13 Release date: 2017-08-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Angew. Chem. Int. Ed. Engl., 56, 2017
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2016-08-13
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