Campylobacter jejuni strain:RM1285 Genome sequencing and assembly

Campylobacter spp. are responsible for the largest number of foodborne gastrointestinal bacterial infections in the developed world. The majority of these human cases of campylobacteriosis are cause by the species Campylobacter jejuni. Poultry products are a primary environmental pathway by which C. jejuni are introduced into the food supply. However, C. jejuni are nutritionally fastidious micro-anaerobes making them unlikely candidates to persist in the environment in sufficient numbers to cause such a large amount of human disease. In this study we fully sequenced and annotated C. jejuni strain RM1285 an environmental isolate from chicken that has revealed unique characteristics. Morphologically, RM1285 is rod shaped compared to the spiral form most common to other C. jejuni strains. Additionally, strain RM1285 has demonstrated increased resistance to inactivation by high hydrostatic pressure compared to other C. jejuni strains.

弯曲菌属（Campylobacter spp.）是造成发达国家食源性胃肠细菌感染数量最多的病原体。其中，绝大多数人类弯曲菌病病例是由空肠弯曲菌（Campylobacter jejuni）引起的。家禽产品是空肠弯曲菌进入食物供应的主要环境途径。然而，空肠弯曲菌作为一种营养要求严格的厌氧性微生物，不太可能以足够数量在环境中持续存在，从而引起大量的人类疾病。在本研究中，我们对来自鸡的环境分离株C. jejuni RM1285进行了全序列测序和注释，该分离株揭示了独特的特征。形态学上，RM1285呈杆状，与大多数其他空肠弯曲菌菌株的螺旋形相比。此外，与大多数其他空肠弯曲菌菌株相比，RM1285菌株表现出对高压失活的更高抵抗力。