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RREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [RNA-seq]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE223879
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To establish molecular pathways disrupted by loss of RREB1 in Purkinje cells, RNA-seq was performed on mRNA isolated from Purkinje cells and differential expression analysis was performed. Cerebella from 3 Rpl22fl/+;PCP2-Cre and 4 Rpl22fl/+;PCP2-CRE;nm3888-/- mice were collected. HA tagged ribosomes were immunoprecipitated from fresh tissue and nascent mRNA transcripts were isolated .
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2024-04-02
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