To examine the global impact of iAs on DNA methylation patterns. Genomic DNA was bisulfite converted and analyzed using Infinium MethylationEPIC BeadChip. Overall design: DNA from NT, iAs-treated, and
We detected the transcriptional alterations and enhancer gain or loss upon depletion of a key epithelial TF, ELF3, and analyzed the molecular events during epithelial-to-mesenchymal transition process
Additional file 2. Turquoise (EMT) subnetwork. The list of genes, module membership, the logarithm of fold change, differential analysis. adj-p.value, and gene-significance statistics.
Castration Resistant Prostate Cancer (CRPC) is thought to be driven by a collaborative mechanism between TNFα/NFκB and TGFβ signaling, leading to inflammation, Epithelial-to-Mesenchymal-Transition (EM
