Human SIRT2 in complex with a specific inhibitor, NPD11033
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Human SIRT2 in complex with a specific inhibitor, NPD11033 Descriptor: (1~{R},9~{S})-11-[(2~{R})-3-[2,4-bis(2-methylbutan-2-yl)phenoxy]-2-oxidanyl-propyl]-7,11-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4-dien-6-one, NAD-dependent protein deacetylase sirtuin-2, ZINC ION Authors: Kudo, N, Ito, A, Yoshida, M. Deposit date: 2017-07-19 Release date: 2018-07-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification of a novel small molecule that inhibits deacetylase but not defatty-acylase reaction catalysed by SIRT2. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018
创建时间：
2017-07-19
