Crystal Structure of bromodomain of human CBP in complex with the inhibitor CZL-046
收藏Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/9j6o
下载链接
链接失效反馈官方服务：
资源简介：
Crystal Structure of bromodomain of human CBP in complex with the inhibitor CZL-046 Descriptor: (3~{S},5~{S})-1-[3,4-bis(fluoranyl)phenyl]-5-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]-3-fluoranyl-pyrrolidin-2-one, CHLORIDE ION, CREB-binding protein Authors: Zhang, Y, Zhang, C, Chen, Z, Yang, H, Huang, X, Li, Y, Xu, Y. Deposit date: 2024-08-16 Release date: 2024-10-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Discovery of CZL-046 with an ( S )-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma. J.Med.Chem., 67, 2024
创建时间：
2024-08-16
