官方服务：
资源简介：
OGT small interfering RNA was transfected into RL95-2 cells to down-regulate O-GlcNAcylation, and gene transcriptional changes were detected by sequencing.
应用场景：
创建时间：
2020-09-16
相关数据集
O-GlcNAcylation: A Morphologic Regulator of Osteoblast Differentiation
To explore the potential mechanisms which O-linked-Nacetylglucosaminylation (O-GlcNAcylation) regulates osteogenesis, a publicly RNA-seq dataset was re-analyzed with literature-mining and showed the p
Mendeley Data70
O-GlcNAcylation drives calcium signaling towards osteoblast differentiation: a bioinformatics-oriented study
Objective: This study aimed to reveal the possible mechanisms by which O-linked-N-acetylglucosaminylation (O-GlcNAcylation) regulates osteoblast differentiation using a series of bioinformatics-orient
Mendeley Data2021-08-02 更新30
Small molecule splicing modulators that disrupt O-GlcNAc homeostasis
O-Linked N-acetylglucosamine (O-GlcNAc) is a nucleocytoplasmic post-translational modification that is tightly regulated by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Dysregulation of O-GlcNAc
NIAID Data Ecosystem20
Perturbation of O-GlcNAcylation homeostasis in Drosophila early embryos influences neurodevelopment by tuning facultative heterochromatin formation
Protein O-GlcNAcylation is a monosaccharide posttranslational modification maintained by two evolutionarily conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Mutations in human OGT
NIAID Data Ecosystem40
Jun O-GlcNAcylatSchwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUNion promotes peripheral nerve remyelination after nerve injury. Jun O-GlcNAcylatSchwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUNion promotes peripheral nerve remyelination after nerve injury
To uncover abnormally regulated genes in OGT-KO SCs, we performed gene expression profiling experiments using sciatic nerves from 1-month-old OGT-SCKO and wildtype mice. Overall design: Gene expressio
NIAID Data Ecosystem30
