Despite the identical FL8 epitope, only a small proportion (23%) of these HIV-1 isolates induced optimal CTL recognition and antiviral efficacy.

The results from the Viral Suppression Assay and Live Virus Elispot in Figure 3 and IFNγ ELISPOT and CTL Lysis assays in Figure 4 are summarised with +++ for optimal, ++ for impaired, + for severely impaired and − for abolished epitope processing and CTL antiviral efficacy.