Data for: Genetic variants underlying human bisexual behavior are reproductively advantageous

Because human same-sex sexual behavior (SSB) is heritable and leads to
fewer offspring, how SSB-associated alleles have persisted and whether
they will remain in human populations are of interest. Using the UK
Biobank, we address these questions separately for bisexual behavior (BSB)
and exclusive SSB (eSSB) after confirming their genetic distinction. We
discover that male BSB is genetically positively correlated with the
number of offspring. This unexpected phenomenon is attributable to the
horizontal pleiotropy of male risk-taking behavior-associated alleles,
because male risk-taking behavior is genetically positively correlated
with both BSB and the number of offspring and because genetically
controlling male risk-taking behavior abolishes the genetic correlation
between male BSB and the number of offspring. By contrast, eSSB is
genetically negatively correlated with the number of offspring. Our
results suggest that male BSB-associated alleles are likely reproductively
advantageous, which may explain their past persistence and predict their
future maintenance, and that eSSB-associated alleles are likely being
selected against at present.