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RNA Sequencing Analysis of Pam3CSK4-stimulated BMDMs with or without Dopamine (DA)

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133316
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Mice Pam3CSK4-stimulated bone marrow derived macrophages with DA or not genome.Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the most prominent downregulated pathway upon DA treatment was NF-kappaB signaling pathway. Consistently, the heatmap analysis displayed significantly decreased expression in many genes associated with NF-kappaB signaling and inflammation, such as Il6, Tnf, Il12b, Il1b, and Ccl5 Pam3CSK4-stimulated BMDMs with or without DA mRNA profiles were generated by deep sequencing, in triplicate, using BGISEQ-500
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2020-02-14
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