five

X-ray crystal structure of wild type HIV-1 protease in complex with GRL-097

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Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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X-ray crystal structure of wild type HIV-1 protease in complex with GRL-097 Descriptor: (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-(4-methoxyphenyl)butan-2-yl]carbamate, HIV-1 protease Authors: Yedidi, R.S, Hayashi, H, Aoki, M, Das, D, Ghosh, A.K, Mitsuya, H. Deposit date: 2015-07-20 Release date: 2016-01-13 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2 Å) Cite: C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir. J.Virol., 90, 2015
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2015-07-20
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