A three component mix of thioredoxin-L2 antigens elicits broadly neutralizing responses against oncogenic human papillomaviruses.
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The epitope sequence was provided in Rubio et al. Vaccine 2009 27:1949 [PMID 19368776]. The L2 pseudovirion-based neutralization assay (L2-PBNA) was used to determine immunogenicity and cross-reactivity of peptide 20-38 constructs. Multivalent immunogens containing combinations or mixtures of the 20-38 epitope from related HPV types also induced reactivity against the antigen.
提供机构：
IEDB
创建时间：
2014-01-01
