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Crystal Structure of Unlinked NS2B_NS3 Protease from Zika Virus in Complex with Inhibitor MI-2113

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Protein Data Bank Japan2024-11-20 更新2026-04-25 收录
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Crystal Structure of Unlinked NS2B_NS3 Protease from Zika Virus in Complex with Inhibitor MI-2113 Descriptor: (2~{R})-6-[[(2~{S})-6-azanyl-2-[[(2~{S})-6-azanyl-2-(2-phenylethanoylamino)hexanoyl]amino]hexanoyl]amino]-2-carbamimidamido-hexanoic acid, Serine protease NS3, Serine protease subunit NS2B Authors: Huber, S, Steinmetzer, T. Deposit date: 2022-04-19 Release date: 2022-12-28 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Thermodynamic characterization of a macrocyclic Zika virus NS2B/NS3 protease inhibitor and its acyclic analogs. Arch Pharm, 356, 2023

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2022-04-19
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