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Structure of the Wnt deacylase Notum in complex with isoquinoline 45

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Structure of the Wnt deacylase Notum in complex with isoquinoline 45 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... Authors: Vecchia, L, Zhao, Y, Ruza, R.R, Jones, E.Y. Deposit date: 2019-04-02 Release date: 2019-05-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen. Medchemcomm, 10, 2019

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2019-04-02
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