Total and GC B cells with or without miR-146a

To examine the impact of miR-146a on GC B cell development, transcriptomic profilings of total B cells isolated from unimmunized mice with B cell-specific deletion of miR-146a (B-KO) or GC B cells isolated from B-KO mice upon sheep red blood cell (SRBC) immunization were done. Overall design: B cells or GC B cells isolated from mice with B cell-specific deletion of miR-146a with or without SRBC immunization