Profiling of gene expression in the brain associated with anxiety-related behaviors in the chronic phase following cranial irradiation

By using RNA sequencing (RNA-seq), we analyzed gene expression profiles in the cortex and hippocampus of the adult brain to demonstrate the molecular mechanisms of radiation-induced brain dysfunction. Comparative gene expression profiling analysis of RNA-seq data in hippocampus and cortex of mice brain at 3 months after cranial irradiation