Crystal Structure of a Naphthyridine Inhibitor of Human TGF-beta Type I Receptor

Crystal Structure of a Naphthyridine Inhibitor of Human TGF-beta Type I Receptor Descriptor: 2-[5-(6-METHYLPYRIDIN-2-YL)-2,3-DIHYDRO-1H-PYRAZOL-4-YL]-1,5-NAPHTHYRIDINE, TGF-beta receptor type I Authors: Gellibert, F, Woolven, J, Fouchet, M.-H, Mathews, N, Goodland, H, Lovegrove, V, Laroze, A, Nguyen, V.-L, Sautet, S, Wang, R, Janson, C, Smith, W, Krysa, G, Boullay, V, de Gouville, A.-C, Huet, S, Hartley, D. Deposit date: 2004-04-07 Release date: 2004-08-31 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification of 1,5-Naphthyridine Derivatives as a Novel Series of Potent and Selective TGF-beta Type I Receptor Inhibitors. J.Med.Chem., 47, 2004